Recombinant multi-species CRDL2/ CHRDL2/ BNF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CHRDL2/CHRDL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHRDL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CHRDL2, gene name: CHRDL2, also named as BNF1, CHL2. This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0778-Ag-1Human CHRDL2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0778-Ag-1Rat CHRDL2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0778-Ag-1Mouse CHRDL2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0778-Ag-1Cynomolgus/ Rhesus macaque CHRDL2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0778-Ag-1Feline CHRDL2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0778-Ag-1Canine CHRDL2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0778-Ag-1Bovine CHRDL2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0778-Ag-1Equine CHRDL2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-SE0778-Ag, GM-Tg-rg-SE0778-Ag, GM-Tg-mg-SE0778-Ag, GM-Tg-cynog-SE0778-Ag,
GM-Tg-felg-SE0778-Ag, GM-Tg-cang-SE0778-Ag, GM-Tg-bovg-SE0778-Ag, GM-Tg-equg-SE0778-Ag-1
Products Name CHRDL2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCHRDL2
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHRDL2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.