Recombinant multi-species GDF1/ CERS1/ CHTD6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to GDF1/GDF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GDF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GDF1, gene name: GDF1, also named as CERS1, CHTD6, DORV, DTGA3, LAG1, LASS1, RAI, UOG1. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0938-Ag-1Human GDF1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0938-Ag-1Rat GDF1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0938-Ag-1Mouse GDF1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0938-Ag-1Cynomolgus/ Rhesus macaque GDF1 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0938-Ag-1Feline GDF1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0938-Ag-1Canine GDF1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0938-Ag-1Bovine GDF1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0938-Ag-1Equine GDF1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-SE0938-Ag, GM-Tg-rg-SE0938-Ag, GM-Tg-mg-SE0938-Ag, GM-Tg-cynog-SE0938-Ag,
GM-Tg-felg-SE0938-Ag, GM-Tg-cang-SE0938-Ag, GM-Tg-bovg-SE0938-Ag, GM-Tg-equg-SE0938-Ag-1
Products Name GDF1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameGDF1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GDF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.