Recombinant multi-species KAZD1/ KAZALD1/ BONO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KAZALD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: KAZALD1, gene name: KAZALD1, also named as BONO1, FKSG28, FKSG40, IGFBP-rP10. This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. The protein contains an insulin growth factor-binding domain in its N-terminal region, a Kazal-type serine protease inhibitor and follistatin-like domain in its central region, and an immunoglobulin-like domain in its C-terminal region. Studies of the mouse ortholog suggest that this protein may function in bone development and bone regeneration. This gene is hypomethylated and over-expressed in high-grade glioma compared to low-grade glioma, and thus the hypomethylated gene may be associated with cell proliferation and the shorter survival of patients with high-grade glioma. It is also one of numerous genes found to be deleted in a novel 5.54 Mb interstitial deletion, which is associated with multiple congenital anomalies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1044-Ag-1	Human KAZALD1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1044-Ag-1	Rat KAZALD1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1044-Ag-1	Mouse KAZALD1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1044-Ag-1	Cynomolgus/ Rhesus macaque KAZALD1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1044-Ag-1	Feline KAZALD1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1044-Ag-1	Canine KAZALD1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1044-Ag-1	Bovine KAZALD1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1044-Ag-1	Equine KAZALD1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1044-Ag, GM-Tg-rg-SE1044-Ag, GM-Tg-mg-SE1044-Ag, GM-Tg-cynog-SE1044-Ag, GM-Tg-felg-SE1044-Ag, GM-Tg-cang-SE1044-Ag, GM-Tg-bovg-SE1044-Ag, GM-Tg-equg-SE1044-Ag-1
Products Name	KAZALD1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	KAZALD1
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KAZALD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.