Recombinant multi-species LOXL1/ LOL/ LOXL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LOXL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: LOXL1, gene name: LOXL1, also named as LOL, LOXL. This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-SE1077-Ag-1 | Human LOXL1 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-SE1077-Ag-1 | Rat LOXL1 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-SE1077-Ag-1 | Mouse LOXL1 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-SE1077-Ag-1 | Cynomolgus/ Rhesus macaque LOXL1 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-SE1077-Ag-1 | Feline LOXL1 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-SE1077-Ag-1 | Canine LOXL1 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-SE1077-Ag-1 | Bovine LOXL1 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-SE1077-Ag-1 | Equine LOXL1 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-SE1077-Ag, GM-Tg-rg-SE1077-Ag, GM-Tg-mg-SE1077-Ag, GM-Tg-cynog-SE1077-Ag, GM-Tg-felg-SE1077-Ag, GM-Tg-cang-SE1077-Ag, GM-Tg-bovg-SE1077-Ag, GM-Tg-equg-SE1077-Ag-1 |
Products Name | LOXL1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | LOXL1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LOXL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
