Recombinant multi-species PG12B/ PLA2G12B/ FKSG71 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PLA2G12B/PLA2G12B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLA2G12B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PLA2G12B, gene name: PLA2G12B, also named as FKSG71, GXIIB, GXIIIsPLA2, PLA2G13, sPLA2-GXIIB. The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE1191-Ag-1Human PLA2G12B proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1191-Ag-1Rat PLA2G12B proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1191-Ag-1Mouse PLA2G12B proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1191-Ag-1Cynomolgus/ Rhesus macaque PLA2G12B proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE1191-Ag-1Feline PLA2G12B proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE1191-Ag-1Canine PLA2G12B proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1191-Ag-1Bovine PLA2G12B proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1191-Ag-1Equine PLA2G12B proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE1191-Ag, GM-Tg-rg-SE1191-Ag, GM-Tg-mg-SE1191-Ag, GM-Tg-cynog-SE1191-Ag,
GM-Tg-felg-SE1191-Ag, GM-Tg-cang-SE1191-Ag, GM-Tg-bovg-SE1191-Ag, GM-Tg-equg-SE1191-Ag-1
Products Name PLA2G12B protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePLA2G12B
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLA2G12B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.