Recombinant multi-species MSH3/ DUP/ FAP4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MSH3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MSH3, gene name: MSH3, also named as DUP, FAP4, MRP1. The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1464-Ag-1	Human MSH3 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1464-Ag-1	Rat MSH3 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1464-Ag-1	Mouse MSH3 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1464-Ag-1	Cynomolgus/ Rhesus macaque MSH3 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1464-Ag-1	Feline MSH3 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1464-Ag-1	Canine MSH3 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1464-Ag-1	Bovine MSH3 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1464-Ag-1	Equine MSH3 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1464-Ag, GM-Tg-rg-SE1464-Ag, GM-Tg-mg-SE1464-Ag, GM-Tg-cynog-SE1464-Ag, GM-Tg-felg-SE1464-Ag, GM-Tg-cang-SE1464-Ag, GM-Tg-bovg-SE1464-Ag, GM-Tg-equg-SE1464-Ag-1
Products Name	MSH3 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	MSH3
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MSH3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.