Recombinant multi-species MSH3/ DUP/ FAP4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to MSH3/MSH3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MSH3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MSH3, gene name: MSH3, also named as DUP, FAP4, MRP1. The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE1464-Ag-1Human MSH3 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1464-Ag-1Rat MSH3 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1464-Ag-1Mouse MSH3 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1464-Ag-1Cynomolgus/ Rhesus macaque MSH3 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE1464-Ag-1Feline MSH3 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE1464-Ag-1Canine MSH3 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1464-Ag-1Bovine MSH3 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1464-Ag-1Equine MSH3 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE1464-Ag, GM-Tg-rg-SE1464-Ag, GM-Tg-mg-SE1464-Ag, GM-Tg-cynog-SE1464-Ag,
GM-Tg-felg-SE1464-Ag, GM-Tg-cang-SE1464-Ag, GM-Tg-bovg-SE1464-Ag, GM-Tg-equg-SE1464-Ag-1
Products Name MSH3 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameMSH3
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MSH3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.