Recombinant multi-species BMAL1/ ARNTL/ BMAL1c protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ARNTL/ARNTL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARNTL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ARNTL, gene name: ARNTL, also named as BMAL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021].

Order information


* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE1499-Ag-1Human ARNTL proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1499-Ag-1Rat ARNTL proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1499-Ag-1Mouse ARNTL proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1499-Ag-1Cynomolgus/ Rhesus macaque ARNTL proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE1499-Ag-1Feline ARNTL proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE1499-Ag-1Canine ARNTL proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1499-Ag-1Bovine ARNTL proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1499-Ag-1Equine ARNTL proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE1499-Ag, GM-Tg-rg-SE1499-Ag, GM-Tg-mg-SE1499-Ag, GM-Tg-cynog-SE1499-Ag,
GM-Tg-felg-SE1499-Ag, GM-Tg-cang-SE1499-Ag, GM-Tg-bovg-SE1499-Ag, GM-Tg-equg-SE1499-Ag-1
Products Name ARNTL protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameARNTL
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARNTL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.