Recombinant multi-species BMAL1/ ARNTL/ BMAL1c protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARNTL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ARNTL, gene name: ARNTL, also named as BMAL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1499-Ag-1	Human ARNTL protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1499-Ag-1	Rat ARNTL protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1499-Ag-1	Mouse ARNTL protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1499-Ag-1	Cynomolgus/ Rhesus macaque ARNTL protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1499-Ag-1	Feline ARNTL protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1499-Ag-1	Canine ARNTL protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1499-Ag-1	Bovine ARNTL protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1499-Ag-1	Equine ARNTL protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1499-Ag, GM-Tg-rg-SE1499-Ag, GM-Tg-mg-SE1499-Ag, GM-Tg-cynog-SE1499-Ag, GM-Tg-felg-SE1499-Ag, GM-Tg-cang-SE1499-Ag, GM-Tg-bovg-SE1499-Ag, GM-Tg-equg-SE1499-Ag-1
Products Name	ARNTL protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ARNTL
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARNTL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.