Recombinant multi-species PDC6I/ PDCD6IP/ AIP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDCD6IP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDCD6IP, gene name: PDCD6IP, also named as AIP1, ALIX, DRIP4, HP95. This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1594-Ag-1	Human PDCD6IP protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1594-Ag-1	Rat PDCD6IP protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1594-Ag-1	Mouse PDCD6IP protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1594-Ag-1	Cynomolgus/ Rhesus macaque PDCD6IP protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1594-Ag-1	Feline PDCD6IP protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1594-Ag-1	Canine PDCD6IP protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1594-Ag-1	Bovine PDCD6IP protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1594-Ag-1	Equine PDCD6IP protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1594-Ag, GM-Tg-rg-SE1594-Ag, GM-Tg-mg-SE1594-Ag, GM-Tg-cynog-SE1594-Ag, GM-Tg-felg-SE1594-Ag, GM-Tg-cang-SE1594-Ag, GM-Tg-bovg-SE1594-Ag, GM-Tg-equg-SE1594-Ag-1
Products Name	PDCD6IP protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PDCD6IP
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDCD6IP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.