Recombinant multi-species HNF1A/ HNF-1A/ HNF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNF1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HNF1A, gene name: HNF1A, also named as HNF-1A, HNF1, HNF4A, IDDM20, LFB1, MODY3, TCF-1, TCF1. The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T03556-Ag-1Human HNF1A proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T03556-Ag-1Rat HNF1A proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T03556-Ag-1Mouse HNF1A proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T03556-Ag-1Cynomolgus/ Rhesus macaque HNF1A proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T03556-Ag-1Feline HNF1A proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T03556-Ag-1Canine HNF1A proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T03556-Ag-1Bovine HNF1A proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T03556-Ag-1Equine HNF1A proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T03556-Ag, GM-Tg-rg-T03556-Ag, GM-Tg-mg-T03556-Ag, GM-Tg-cynog-T03556-Ag,
GM-Tg-felg-T03556-Ag, GM-Tg-cang-T03556-Ag, GM-Tg-bovg-T03556-Ag, GM-Tg-equg-T03556-Ag-1
Products Name HNF1A protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHNF1A
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNF1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.