Recombinant multi-species PDE8A/ PDE8/ HsT19550 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PDE8/PDE8A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE8/PDE8A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDE8, gene name: PDE8A, also named as HsT19550. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T05904-Ag-1Human PDE8/PDE8A proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T05904-Ag-1Rat PDE8/PDE8A proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T05904-Ag-1Mouse PDE8/PDE8A proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T05904-Ag-1Cynomolgus/ Rhesus macaque PDE8/PDE8A proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T05904-Ag-1Feline PDE8/PDE8A proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T05904-Ag-1Canine PDE8/PDE8A proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T05904-Ag-1Bovine PDE8/PDE8A proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T05904-Ag-1Equine PDE8/PDE8A proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T05904-Ag, GM-Tg-rg-T05904-Ag, GM-Tg-mg-T05904-Ag, GM-Tg-cynog-T05904-Ag,
GM-Tg-felg-T05904-Ag, GM-Tg-cang-T05904-Ag, GM-Tg-bovg-T05904-Ag, GM-Tg-equg-T05904-Ag-1
Products Name PDE8/PDE8A protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePDE8
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE8/PDE8A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.