Recombinant multi-species CP2A6/ CYP2A6/ CPA6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP2A6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CYP2A6, gene name: CYP2A6, also named as CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB. This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T06455-Ag-1	Human CYP2A6 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T06455-Ag-1	Rat CYP2A6 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T06455-Ag-1	Mouse CYP2A6 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T06455-Ag-1	Cynomolgus/ Rhesus macaque CYP2A6 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T06455-Ag-1	Feline CYP2A6 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T06455-Ag-1	Canine CYP2A6 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T06455-Ag-1	Bovine CYP2A6 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T06455-Ag-1	Equine CYP2A6 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T06455-Ag, GM-Tg-rg-T06455-Ag, GM-Tg-mg-T06455-Ag, GM-Tg-cynog-T06455-Ag, GM-Tg-felg-T06455-Ag, GM-Tg-cang-T06455-Ag, GM-Tg-bovg-T06455-Ag, GM-Tg-equg-T06455-Ag-1
Products Name	CYP2A6 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	CYP2A6
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP2A6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.