Recombinant multi-species IL18/ IGIF/ IL-18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IL18, gene name: IL18, also named as IGIF, IL-18, IL-1g, IL1F4. The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T06671-Ag-1	Human IL18 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T06671-Ag-1	Rat IL18 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T06671-Ag-1	Mouse IL18 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T06671-Ag-1	Cynomolgus/ Rhesus macaque IL18 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T06671-Ag-1	Feline IL18 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T06671-Ag-1	Canine IL18 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T06671-Ag-1	Bovine IL18 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T06671-Ag-1	Equine IL18 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T06671-Ag, GM-Tg-rg-T06671-Ag, GM-Tg-mg-T06671-Ag, GM-Tg-cynog-T06671-Ag, GM-Tg-felg-T06671-Ag, GM-Tg-cang-T06671-Ag, GM-Tg-bovg-T06671-Ag, GM-Tg-equg-T06671-Ag-1
Products Name	IL18 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	IL18
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL18 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.