Recombinant multi-species PDE5A/ CGB-PDE/ CN5A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE5A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDE5A, gene name: PDE5A, also named as CGB-PDE, CN5A, PDE5. This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T07663-Ag-1	Human PDE5A protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T07663-Ag-1	Rat PDE5A protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T07663-Ag-1	Mouse PDE5A protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T07663-Ag-1	Cynomolgus/ Rhesus macaque PDE5A protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T07663-Ag-1	Feline PDE5A protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T07663-Ag-1	Canine PDE5A protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T07663-Ag-1	Bovine PDE5A protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T07663-Ag-1	Equine PDE5A protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T07663-Ag, GM-Tg-rg-T07663-Ag, GM-Tg-mg-T07663-Ag, GM-Tg-cynog-T07663-Ag, GM-Tg-felg-T07663-Ag, GM-Tg-cang-T07663-Ag, GM-Tg-bovg-T07663-Ag, GM-Tg-equg-T07663-Ag-1
Products Name	PDE5A protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PDE5A
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE5A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.