Recombinant multi-species IL10/ CSIF/ GVHDS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IL10, gene name: IL10, also named as CSIF, GVHDS, IL-10A, TGIF, IL10. The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020].

Order information

* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T09092-Ag-1	Human IL10 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T09092-Ag-1	Rat IL10 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T09092-Ag-1	Mouse IL10 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T09092-Ag-1	Cynomolgus/ Rhesus macaque IL10 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T09092-Ag-1	Feline IL10 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T09092-Ag-1	Canine IL10 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T09092-Ag-1	Bovine IL10 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T09092-Ag-1	Equine IL10 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T09092-Ag, GM-Tg-rg-T09092-Ag, GM-Tg-mg-T09092-Ag, GM-Tg-cynog-T09092-Ag, GM-Tg-felg-T09092-Ag, GM-Tg-cang-T09092-Ag, GM-Tg-bovg-T09092-Ag, GM-Tg-equg-T09092-Ag-1
Products Name	IL10 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	IL10
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.