Recombinant multi-species VKOR1/ VKORC1/ EDTP308 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VKORC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: VKORC1, gene name: VKORC1, also named as EDTP308, MST134, MST576, VKCFD2, VKOR. This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T11843-Ag-1	Human VKORC1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T11843-Ag-1	Rat VKORC1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T11843-Ag-1	Mouse VKORC1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T11843-Ag-1	Cynomolgus/ Rhesus macaque VKORC1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T11843-Ag-1	Feline VKORC1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T11843-Ag-1	Canine VKORC1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T11843-Ag-1	Bovine VKORC1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T11843-Ag-1	Equine VKORC1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T11843-Ag, GM-Tg-rg-T11843-Ag, GM-Tg-mg-T11843-Ag, GM-Tg-cynog-T11843-Ag, GM-Tg-felg-T11843-Ag, GM-Tg-cang-T11843-Ag, GM-Tg-bovg-T11843-Ag, GM-Tg-equg-T11843-Ag-1
Products Name	VKORC1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	VKORC1
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VKORC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.