Recombinant multi-species PTN11/ PTPN11/ BPTP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTPN11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PTPN11, gene name: PTPN11, also named as BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T13057-Ag-1	Human PTPN11 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T13057-Ag-1	Rat PTPN11 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T13057-Ag-1	Mouse PTPN11 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T13057-Ag-1	Cynomolgus/ Rhesus macaque PTPN11 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T13057-Ag-1	Feline PTPN11 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T13057-Ag-1	Canine PTPN11 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T13057-Ag-1	Bovine PTPN11 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T13057-Ag-1	Equine PTPN11 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T13057-Ag, GM-Tg-rg-T13057-Ag, GM-Tg-mg-T13057-Ag, GM-Tg-cynog-T13057-Ag, GM-Tg-felg-T13057-Ag, GM-Tg-cang-T13057-Ag, GM-Tg-bovg-T13057-Ag, GM-Tg-equg-T13057-Ag-1
Products Name	PTPN11 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PTPN11
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTPN11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.