Recombinant multi-species IL12A/ CLMF/ IL-12A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL12A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IL12A, gene name: IL12A, also named as CLMF, IL-12A, NFSK, NKSF1, P35. This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T13251-Ag-1Human IL12A proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T13251-Ag-1Rat IL12A proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T13251-Ag-1Mouse IL12A proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T13251-Ag-1Cynomolgus/ Rhesus macaque IL12A proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T13251-Ag-1Feline IL12A proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T13251-Ag-1Canine IL12A proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T13251-Ag-1Bovine IL12A proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T13251-Ag-1Equine IL12A proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T13251-Ag, GM-Tg-rg-T13251-Ag, GM-Tg-mg-T13251-Ag, GM-Tg-cynog-T13251-Ag,
GM-Tg-felg-T13251-Ag, GM-Tg-cang-T13251-Ag, GM-Tg-bovg-T13251-Ag, GM-Tg-equg-T13251-Ag-1
Products Name IL12A protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameIL12A
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL12A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.