Recombinant multi-species PIN1/ DOD/ UBL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PIN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PIN1, gene name: PIN1, also named as DOD, UBL5. Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T16308-Ag-1Human PIN1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T16308-Ag-1Rat PIN1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T16308-Ag-1Mouse PIN1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T16308-Ag-1Cynomolgus/ Rhesus macaque PIN1 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T16308-Ag-1Feline PIN1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T16308-Ag-1Canine PIN1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T16308-Ag-1Bovine PIN1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T16308-Ag-1Equine PIN1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T16308-Ag, GM-Tg-rg-T16308-Ag, GM-Tg-mg-T16308-Ag, GM-Tg-cynog-T16308-Ag,
GM-Tg-felg-T16308-Ag, GM-Tg-cang-T16308-Ag, GM-Tg-bovg-T16308-Ag, GM-Tg-equg-T16308-Ag-1
Products Name PIN1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePIN1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PIN1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.