Recombinant multi-species CDN1C/ CDKN1C/ BWCR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CDKN1C/CDKN1C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDKN1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CDKN1C, gene name: CDKN1C, also named as BWCR, BWS, KIP2, WBS, p57, p57Kip2. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T16459-Ag-1Human CDKN1C proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T16459-Ag-1Rat CDKN1C proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T16459-Ag-1Mouse CDKN1C proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T16459-Ag-1Cynomolgus/ Rhesus macaque CDKN1C proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T16459-Ag-1Feline CDKN1C proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T16459-Ag-1Canine CDKN1C proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T16459-Ag-1Bovine CDKN1C proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T16459-Ag-1Equine CDKN1C proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T16459-Ag, GM-Tg-rg-T16459-Ag, GM-Tg-mg-T16459-Ag, GM-Tg-cynog-T16459-Ag,
GM-Tg-felg-T16459-Ag, GM-Tg-cang-T16459-Ag, GM-Tg-bovg-T16459-Ag, GM-Tg-equg-T16459-Ag-1
Products Name CDKN1C protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCDKN1C
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDKN1C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.