Recombinant multi-species DYR/ DHFR/ DHFRP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHFR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DHFR, gene name: DHFR, also named as DHFRP1, DYR. Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T17345-Ag-1	Human DHFR protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T17345-Ag-1	Rat DHFR protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T17345-Ag-1	Mouse DHFR protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T17345-Ag-1	Cynomolgus/ Rhesus macaque DHFR protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T17345-Ag-1	Feline DHFR protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T17345-Ag-1	Canine DHFR protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T17345-Ag-1	Bovine DHFR protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T17345-Ag-1	Equine DHFR protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T17345-Ag, GM-Tg-rg-T17345-Ag, GM-Tg-mg-T17345-Ag, GM-Tg-cynog-T17345-Ag, GM-Tg-felg-T17345-Ag, GM-Tg-cang-T17345-Ag, GM-Tg-bovg-T17345-Ag, GM-Tg-equg-T17345-Ag-1
Products Name	DHFR protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	DHFR
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHFR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.