Recombinant multi-species LATS2/ KPM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to LATS2/LATS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LATS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: LATS2, gene name: LATS2, also named as KPM. This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T18390-Ag-1Human LATS2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T18390-Ag-1Rat LATS2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T18390-Ag-1Mouse LATS2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T18390-Ag-1Cynomolgus/ Rhesus macaque LATS2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T18390-Ag-1Feline LATS2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T18390-Ag-1Canine LATS2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T18390-Ag-1Bovine LATS2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T18390-Ag-1Equine LATS2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T18390-Ag, GM-Tg-rg-T18390-Ag, GM-Tg-mg-T18390-Ag, GM-Tg-cynog-T18390-Ag,
GM-Tg-felg-T18390-Ag, GM-Tg-cang-T18390-Ag, GM-Tg-bovg-T18390-Ag, GM-Tg-equg-T18390-Ag-1
Products Name LATS2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameLATS2
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LATS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.