Recombinant multi-species TNNI3/ CMD1FF/ CMD2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNI3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TNNI3, gene name: TNNI3, also named as CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19. [provided by RefSeq, Aug 2020].

Order information

* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T20186-Ag-1	Human TNNI3 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T20186-Ag-1	Rat TNNI3 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T20186-Ag-1	Mouse TNNI3 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T20186-Ag-1	Cynomolgus/ Rhesus macaque TNNI3 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T20186-Ag-1	Feline TNNI3 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T20186-Ag-1	Canine TNNI3 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T20186-Ag-1	Bovine TNNI3 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T20186-Ag-1	Equine TNNI3 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T20186-Ag, GM-Tg-rg-T20186-Ag, GM-Tg-mg-T20186-Ag, GM-Tg-cynog-T20186-Ag, GM-Tg-felg-T20186-Ag, GM-Tg-cang-T20186-Ag, GM-Tg-bovg-T20186-Ag, GM-Tg-equg-T20186-Ag-1
Products Name	TNNI3 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	TNNI3
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNI3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.