Recombinant multi-species MGMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MGMT, gene name: MGMT, also named as . Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T24587-Ag-1	Human MGMT protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T24587-Ag-1	Rat MGMT protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T24587-Ag-1	Mouse MGMT protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T24587-Ag-1	Cynomolgus/ Rhesus macaque MGMT protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T24587-Ag-1	Feline MGMT protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T24587-Ag-1	Canine MGMT protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T24587-Ag-1	Bovine MGMT protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T24587-Ag-1	Equine MGMT protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T24587-Ag, GM-Tg-rg-T24587-Ag, GM-Tg-mg-T24587-Ag, GM-Tg-cynog-T24587-Ag, GM-Tg-felg-T24587-Ag, GM-Tg-cang-T24587-Ag, GM-Tg-bovg-T24587-Ag, GM-Tg-equg-T24587-Ag-1
Products Name	MGMT protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	MGMT
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGMT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.