Recombinant multi-species EDN1/ ARCND3/ ET1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to EDN1/EDN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EDN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: EDN1, gene name: EDN1, also named as ARCND3, ET1, HDLCQ7, PPET1, QME. This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T25076-Ag-1Human EDN1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T25076-Ag-1Rat EDN1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T25076-Ag-1Mouse EDN1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T25076-Ag-1Cynomolgus/ Rhesus macaque EDN1 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T25076-Ag-1Feline EDN1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T25076-Ag-1Canine EDN1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T25076-Ag-1Bovine EDN1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T25076-Ag-1Equine EDN1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T25076-Ag, GM-Tg-rg-T25076-Ag, GM-Tg-mg-T25076-Ag, GM-Tg-cynog-T25076-Ag,
GM-Tg-felg-T25076-Ag, GM-Tg-cang-T25076-Ag, GM-Tg-bovg-T25076-Ag, GM-Tg-equg-T25076-Ag-1
Products Name EDN1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameEDN1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EDN1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.