Recombinant multi-species RUNX3/ AML2/ CBFA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to RUNX3/RUNX3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RUNX3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: RUNX3, gene name: RUNX3, also named as AML2, CBFA3, PEBP2aC. This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T29630-Ag-1Human RUNX3 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T29630-Ag-1Rat RUNX3 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T29630-Ag-1Mouse RUNX3 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T29630-Ag-1Cynomolgus/ Rhesus macaque RUNX3 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T29630-Ag-1Feline RUNX3 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T29630-Ag-1Canine RUNX3 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T29630-Ag-1Bovine RUNX3 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T29630-Ag-1Equine RUNX3 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T29630-Ag, GM-Tg-rg-T29630-Ag, GM-Tg-mg-T29630-Ag, GM-Tg-cynog-T29630-Ag,
GM-Tg-felg-T29630-Ag, GM-Tg-cang-T29630-Ag, GM-Tg-bovg-T29630-Ag, GM-Tg-equg-T29630-Ag-1
Products Name RUNX3 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameRUNX3
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RUNX3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.