Recombinant multi-species IL6/ BSF-2/ BSF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IL6, gene name: IL6, also named as BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6. This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T32578-Ag-1	Human IL6 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T32578-Ag-1	Rat IL6 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T32578-Ag-1	Mouse IL6 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T32578-Ag-1	Cynomolgus/ Rhesus macaque IL6 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T32578-Ag-1	Feline IL6 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T32578-Ag-1	Canine IL6 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T32578-Ag-1	Bovine IL6 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T32578-Ag-1	Equine IL6 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T32578-Ag, GM-Tg-rg-T32578-Ag, GM-Tg-mg-T32578-Ag, GM-Tg-cynog-T32578-Ag, GM-Tg-felg-T32578-Ag, GM-Tg-cang-T32578-Ag, GM-Tg-bovg-T32578-Ag, GM-Tg-equg-T32578-Ag-1
Products Name	IL6 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	IL6
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.