Recombinant multi-species GDF15/ GDF-15/ MIC-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GDF15 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GDF15, gene name: GDF15, also named as GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T33245-Ag-1	Human GDF15 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T33245-Ag-1	Rat GDF15 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T33245-Ag-1	Mouse GDF15 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T33245-Ag-1	Cynomolgus/ Rhesus macaque GDF15 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T33245-Ag-1	Feline GDF15 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T33245-Ag-1	Canine GDF15 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T33245-Ag-1	Bovine GDF15 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T33245-Ag-1	Equine GDF15 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T33245-Ag, GM-Tg-rg-T33245-Ag, GM-Tg-mg-T33245-Ag, GM-Tg-cynog-T33245-Ag, GM-Tg-felg-T33245-Ag, GM-Tg-cang-T33245-Ag, GM-Tg-bovg-T33245-Ag, GM-Tg-equg-T33245-Ag-1
Products Name	GDF15 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	GDF15
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GDF15 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.