Recombinant multi-species PON1/ ESA/ MVCD5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PON1/PON1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PON1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PON1, gene name: PON1, also named as ESA, MVCD5, PON. This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T34562-Ag-1Human PON1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T34562-Ag-1Rat PON1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T34562-Ag-1Mouse PON1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T34562-Ag-1Cynomolgus/ Rhesus macaque PON1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T34562-Ag-1Feline PON1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T34562-Ag-1Canine PON1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T34562-Ag-1Bovine PON1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T34562-Ag-1Equine PON1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T34562-Ag, GM-Tg-rg-T34562-Ag, GM-Tg-mg-T34562-Ag, GM-Tg-cynog-T34562-Ag,
GM-Tg-felg-T34562-Ag, GM-Tg-cang-T34562-Ag, GM-Tg-bovg-T34562-Ag, GM-Tg-equg-T34562-Ag-1
Products Name PON1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePON1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PON1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.