Recombinant multi-species SMAD3/ HSPC193/ HsT17436 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMAD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SMAD3, gene name: SMAD3, also named as HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3. The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T35445-Ag-1	Human SMAD3 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T35445-Ag-1	Rat SMAD3 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T35445-Ag-1	Mouse SMAD3 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T35445-Ag-1	Cynomolgus/ Rhesus macaque SMAD3 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T35445-Ag-1	Feline SMAD3 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T35445-Ag-1	Canine SMAD3 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T35445-Ag-1	Bovine SMAD3 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T35445-Ag-1	Equine SMAD3 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T35445-Ag, GM-Tg-rg-T35445-Ag, GM-Tg-mg-T35445-Ag, GM-Tg-cynog-T35445-Ag, GM-Tg-felg-T35445-Ag, GM-Tg-cang-T35445-Ag, GM-Tg-bovg-T35445-Ag, GM-Tg-equg-T35445-Ag-1
Products Name	SMAD3 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	SMAD3
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMAD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.