Recombinant multi-species DHSD/ SDHD/ CBT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to SDHD/SDHD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SDHD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SDHD, gene name: SDHD, also named as CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS. This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T39811-Ag-1Human SDHD proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T39811-Ag-1Rat SDHD proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T39811-Ag-1Mouse SDHD proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T39811-Ag-1Cynomolgus/ Rhesus macaque SDHD proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T39811-Ag-1Feline SDHD proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T39811-Ag-1Canine SDHD proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T39811-Ag-1Bovine SDHD proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T39811-Ag-1Equine SDHD proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T39811-Ag, GM-Tg-rg-T39811-Ag, GM-Tg-mg-T39811-Ag, GM-Tg-cynog-T39811-Ag,
GM-Tg-felg-T39811-Ag, GM-Tg-cang-T39811-Ag, GM-Tg-bovg-T39811-Ag, GM-Tg-equg-T39811-Ag-1
Products Name SDHD protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameSDHD
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SDHD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.