Recombinant multi-species BCL6/ BCL-6/ BCL5A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCL-6/BCL6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: BCL-6, gene name: BCL6, also named as BCL5A, LAZ3, ZBTB27, ZNF51, BCL6. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T43548-Ag-1Human BCL-6/BCL6 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T43548-Ag-1Rat BCL-6/BCL6 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T43548-Ag-1Mouse BCL-6/BCL6 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T43548-Ag-1Cynomolgus/ Rhesus macaque BCL-6/BCL6 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T43548-Ag-1Feline BCL-6/BCL6 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T43548-Ag-1Canine BCL-6/BCL6 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T43548-Ag-1Bovine BCL-6/BCL6 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T43548-Ag-1Equine BCL-6/BCL6 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T43548-Ag, GM-Tg-rg-T43548-Ag, GM-Tg-mg-T43548-Ag, GM-Tg-cynog-T43548-Ag,
GM-Tg-felg-T43548-Ag, GM-Tg-cang-T43548-Ag, GM-Tg-bovg-T43548-Ag, GM-Tg-equg-T43548-Ag-1
Products Name BCL-6/BCL6 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameBCL-6
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCL-6/BCL6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.