Recombinant multi-species CDK9/ C-2k/ CDC2L4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CDK9, gene name: CDK9, also named as C-2k, CDC2L4, CTK1, PITALRE, TAK. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T44458-Ag-1	Human CDK9 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T44458-Ag-1	Rat CDK9 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T44458-Ag-1	Mouse CDK9 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T44458-Ag-1	Cynomolgus/ Rhesus macaque CDK9 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T44458-Ag-1	Feline CDK9 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T44458-Ag-1	Canine CDK9 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T44458-Ag-1	Bovine CDK9 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T44458-Ag-1	Equine CDK9 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T44458-Ag, GM-Tg-rg-T44458-Ag, GM-Tg-mg-T44458-Ag, GM-Tg-cynog-T44458-Ag, GM-Tg-felg-T44458-Ag, GM-Tg-cang-T44458-Ag, GM-Tg-bovg-T44458-Ag, GM-Tg-equg-T44458-Ag-1
Products Name	CDK9 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	CDK9
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.