Recombinant multi-species KPCG/ PRKCG/ PKC-gamma protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PRKCG/PRKCG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKCG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PRKCG, gene name: PRKCG, also named as PKC-gamma, PKCC, PKCG, PKCI(3), PKCgamma, SCA14. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T47107-Ag-1Human PRKCG proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T47107-Ag-1Rat PRKCG proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T47107-Ag-1Mouse PRKCG proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T47107-Ag-1Cynomolgus/ Rhesus macaque PRKCG proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T47107-Ag-1Feline PRKCG proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T47107-Ag-1Canine PRKCG proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T47107-Ag-1Bovine PRKCG proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T47107-Ag-1Equine PRKCG proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T47107-Ag, GM-Tg-rg-T47107-Ag, GM-Tg-mg-T47107-Ag, GM-Tg-cynog-T47107-Ag,
GM-Tg-felg-T47107-Ag, GM-Tg-cang-T47107-Ag, GM-Tg-bovg-T47107-Ag, GM-Tg-equg-T47107-Ag-1
Products Name PRKCG protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePRKCG
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKCG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.