Products
Recombinant multi-species HEM3/ HMBS/ PBG-D protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to HMBS/HMBS products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HMBS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: HMBS, gene name: HMBS, also named as PBG-D, PBGD, PORC, UPS. This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-T47466-Ag-1 | Human HMBS protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T47466-Ag-1 | Rat HMBS protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T47466-Ag-1 | Mouse HMBS protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T47466-Ag-1 | Cynomolgus/ Rhesus macaque HMBS protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-T47466-Ag-1 | Feline HMBS protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-T47466-Ag-1 | Canine HMBS protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T47466-Ag-1 | Bovine HMBS protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T47466-Ag-1 | Equine HMBS protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-T47466-Ag, GM-Tg-rg-T47466-Ag, GM-Tg-mg-T47466-Ag, GM-Tg-cynog-T47466-Ag, GM-Tg-felg-T47466-Ag, GM-Tg-cang-T47466-Ag, GM-Tg-bovg-T47466-Ag, GM-Tg-equg-T47466-Ag-1 |
| Products Name | HMBS protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | HMBS |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HMBS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
