Recombinant multi-species SPDEF/ PDEF/ bA375E1.3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to SPDEF/SPDEF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPDEF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SPDEF, gene name: SPDEF, also named as PDEF, bA375E1.3. The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T48518-Ag-1Human SPDEF proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T48518-Ag-1Rat SPDEF proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T48518-Ag-1Mouse SPDEF proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T48518-Ag-1Cynomolgus/ Rhesus macaque SPDEF proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T48518-Ag-1Feline SPDEF proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T48518-Ag-1Canine SPDEF proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T48518-Ag-1Bovine SPDEF proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T48518-Ag-1Equine SPDEF proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T48518-Ag, GM-Tg-rg-T48518-Ag, GM-Tg-mg-T48518-Ag, GM-Tg-cynog-T48518-Ag,
GM-Tg-felg-T48518-Ag, GM-Tg-cang-T48518-Ag, GM-Tg-bovg-T48518-Ag, GM-Tg-equg-T48518-Ag-1
Products Name SPDEF protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameSPDEF
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPDEF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.