Recombinant multi-species E2AK2/ PKR/ EIF2AK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKR/EIF2AK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PKR, gene name: EIF2AK2, also named as EIF2AK1, PKR, PPP1R83, PRKR. The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T51102-Ag-1	Human PKR/EIF2AK2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T51102-Ag-1	Rat PKR/EIF2AK2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T51102-Ag-1	Mouse PKR/EIF2AK2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T51102-Ag-1	Cynomolgus/ Rhesus macaque PKR/EIF2AK2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T51102-Ag-1	Feline PKR/EIF2AK2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T51102-Ag-1	Canine PKR/EIF2AK2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T51102-Ag-1	Bovine PKR/EIF2AK2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T51102-Ag-1	Equine PKR/EIF2AK2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T51102-Ag, GM-Tg-rg-T51102-Ag, GM-Tg-mg-T51102-Ag, GM-Tg-cynog-T51102-Ag, GM-Tg-felg-T51102-Ag, GM-Tg-cang-T51102-Ag, GM-Tg-bovg-T51102-Ag, GM-Tg-equg-T51102-Ag-1
Products Name	PKR/EIF2AK2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PKR
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKR/EIF2AK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.