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Recombinant multi-species CHIO/ CHN2/ ARHGAP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to CHN2/CHN2 products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: CHN2, gene name: CHN2, also named as ARHGAP3, BCH-3, RHOGAP3, CHN2. This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-T52566-Ag-1 | Human CHN2 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T52566-Ag-1 | Rat CHN2 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T52566-Ag-1 | Mouse CHN2 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T52566-Ag-1 | Cynomolgus/ Rhesus macaque CHN2 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-T52566-Ag-1 | Feline CHN2 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-T52566-Ag-1 | Canine CHN2 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T52566-Ag-1 | Bovine CHN2 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T52566-Ag-1 | Equine CHN2 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-T52566-Ag, GM-Tg-rg-T52566-Ag, GM-Tg-mg-T52566-Ag, GM-Tg-cynog-T52566-Ag, GM-Tg-felg-T52566-Ag, GM-Tg-cang-T52566-Ag, GM-Tg-bovg-T52566-Ag, GM-Tg-equg-T52566-Ag-1 |
| Products Name | CHN2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CHN2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
