Recombinant multi-species EGLN2/ HPH-1/ EIT-6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPH-1/EGLN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: HPH-1, gene name: EGLN2, also named as EIT-6, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1. The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-T53904-Ag-1 | Human HPH-1/EGLN2 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T53904-Ag-1 | Rat HPH-1/EGLN2 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T53904-Ag-1 | Mouse HPH-1/EGLN2 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T53904-Ag-1 | Cynomolgus/ Rhesus macaque HPH-1/EGLN2 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-T53904-Ag-1 | Feline HPH-1/EGLN2 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-T53904-Ag-1 | Canine HPH-1/EGLN2 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T53904-Ag-1 | Bovine HPH-1/EGLN2 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T53904-Ag-1 | Equine HPH-1/EGLN2 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-T53904-Ag, GM-Tg-rg-T53904-Ag, GM-Tg-mg-T53904-Ag, GM-Tg-cynog-T53904-Ag, GM-Tg-felg-T53904-Ag, GM-Tg-cang-T53904-Ag, GM-Tg-bovg-T53904-Ag, GM-Tg-equg-T53904-Ag-1 |
Products Name | HPH-1/EGLN2 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | HPH-1 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPH-1/EGLN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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