Recombinant multi-species EGLN2/ HPH-1/ EIT-6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to HPH-1/EGLN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPH-1/EGLN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HPH-1, gene name: EGLN2, also named as EIT-6, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1. The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T53904-Ag-1Human HPH-1/EGLN2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T53904-Ag-1Rat HPH-1/EGLN2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T53904-Ag-1Mouse HPH-1/EGLN2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T53904-Ag-1Cynomolgus/ Rhesus macaque HPH-1/EGLN2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T53904-Ag-1Feline HPH-1/EGLN2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T53904-Ag-1Canine HPH-1/EGLN2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T53904-Ag-1Bovine HPH-1/EGLN2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T53904-Ag-1Equine HPH-1/EGLN2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T53904-Ag, GM-Tg-rg-T53904-Ag, GM-Tg-mg-T53904-Ag, GM-Tg-cynog-T53904-Ag,
GM-Tg-felg-T53904-Ag, GM-Tg-cang-T53904-Ag, GM-Tg-bovg-T53904-Ag, GM-Tg-equg-T53904-Ag-1
Products Name HPH-1/EGLN2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHPH-1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPH-1/EGLN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.