Recombinant multi-species ANFB/ BNP/ NPPB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNP/NPPB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: BNP, gene name: NPPB, also named as BNP. This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T55302-Ag-1	Human BNP/NPPB protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T55302-Ag-1	Rat BNP/NPPB protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T55302-Ag-1	Mouse BNP/NPPB protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T55302-Ag-1	Cynomolgus/ Rhesus macaque BNP/NPPB protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T55302-Ag-1	Feline BNP/NPPB protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T55302-Ag-1	Canine BNP/NPPB protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T55302-Ag-1	Bovine BNP/NPPB protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T55302-Ag-1	Equine BNP/NPPB protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T55302-Ag, GM-Tg-rg-T55302-Ag, GM-Tg-mg-T55302-Ag, GM-Tg-cynog-T55302-Ag, GM-Tg-felg-T55302-Ag, GM-Tg-cang-T55302-Ag, GM-Tg-bovg-T55302-Ag, GM-Tg-equg-T55302-Ag-1
Products Name	BNP/NPPB protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	BNP
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNP/NPPB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.