Recombinant multi-species ZUP1/ C6orf113/ DUB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ZUP1/ZUP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ZUP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ZUP1, gene name: ZUP1, also named as C6orf113, DUB, ZUFSP. This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T57050-Ag-1Human ZUP1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T57050-Ag-1Rat ZUP1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T57050-Ag-1Mouse ZUP1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T57050-Ag-1Cynomolgus/ Rhesus macaque ZUP1 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T57050-Ag-1Feline ZUP1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T57050-Ag-1Canine ZUP1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T57050-Ag-1Bovine ZUP1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T57050-Ag-1Equine ZUP1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T57050-Ag, GM-Tg-rg-T57050-Ag, GM-Tg-mg-T57050-Ag, GM-Tg-cynog-T57050-Ag,
GM-Tg-felg-T57050-Ag, GM-Tg-cang-T57050-Ag, GM-Tg-bovg-T57050-Ag, GM-Tg-equg-T57050-Ag-1
Products Name ZUP1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameZUP1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ZUP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.