Recombinant multi-species GABT/ ABAT/ GABA-AT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABAT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ABAT, gene name: ABAT, also named as GABA-AT, GABAT, NPD009. 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T59045-Ag-1	Human ABAT protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T59045-Ag-1	Rat ABAT protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T59045-Ag-1	Mouse ABAT protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T59045-Ag-1	Cynomolgus/ Rhesus macaque ABAT protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T59045-Ag-1	Feline ABAT protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T59045-Ag-1	Canine ABAT protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T59045-Ag-1	Bovine ABAT protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T59045-Ag-1	Equine ABAT protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T59045-Ag, GM-Tg-rg-T59045-Ag, GM-Tg-mg-T59045-Ag, GM-Tg-cynog-T59045-Ag, GM-Tg-felg-T59045-Ag, GM-Tg-cang-T59045-Ag, GM-Tg-bovg-T59045-Ag, GM-Tg-equg-T59045-Ag-1
Products Name	ABAT protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ABAT
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABAT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.