Recombinant multi-species DHB4/ HSD17B4/ DBP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to HSD17B4/HSD17B4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSD17B4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HSD17B4, gene name: HSD17B4, also named as DBP, MFE-2, MPF-2, PRLTS1, SDR8C1. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T59230-Ag-1Human HSD17B4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T59230-Ag-1Rat HSD17B4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T59230-Ag-1Mouse HSD17B4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T59230-Ag-1Cynomolgus/ Rhesus macaque HSD17B4 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T59230-Ag-1Feline HSD17B4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T59230-Ag-1Canine HSD17B4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T59230-Ag-1Bovine HSD17B4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T59230-Ag-1Equine HSD17B4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T59230-Ag, GM-Tg-rg-T59230-Ag, GM-Tg-mg-T59230-Ag, GM-Tg-cynog-T59230-Ag,
GM-Tg-felg-T59230-Ag, GM-Tg-cang-T59230-Ag, GM-Tg-bovg-T59230-Ag, GM-Tg-equg-T59230-Ag-1
Products Name HSD17B4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHSD17B4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSD17B4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.