Recombinant multi-species PKN1/ DBK/ PAK-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PKN1/PKN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PKN1, gene name: PKN1, also named as DBK, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1. The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T60003-Ag-1Human PKN1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T60003-Ag-1Rat PKN1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T60003-Ag-1Mouse PKN1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T60003-Ag-1Cynomolgus/ Rhesus macaque PKN1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T60003-Ag-1Feline PKN1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T60003-Ag-1Canine PKN1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T60003-Ag-1Bovine PKN1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T60003-Ag-1Equine PKN1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T60003-Ag, GM-Tg-rg-T60003-Ag, GM-Tg-mg-T60003-Ag, GM-Tg-cynog-T60003-Ag,
GM-Tg-felg-T60003-Ag, GM-Tg-cang-T60003-Ag, GM-Tg-bovg-T60003-Ag, GM-Tg-equg-T60003-Ag-1
Products Name PKN1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePKN1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKN1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.