Recombinant multi-species PGH1/ COX-1/ PTGS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX-1/PTGS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: COX-1, gene name: PTGS1, also named as COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS. This is one of two genes encoding similar enzymes that catalyze the conversion of arachidonate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2021].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T60529-Ag-1	Human COX-1/PTGS1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T60529-Ag-1	Rat COX-1/PTGS1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T60529-Ag-1	Mouse COX-1/PTGS1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T60529-Ag-1	Cynomolgus/ Rhesus macaque COX-1/PTGS1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T60529-Ag-1	Feline COX-1/PTGS1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T60529-Ag-1	Canine COX-1/PTGS1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T60529-Ag-1	Bovine COX-1/PTGS1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T60529-Ag-1	Equine COX-1/PTGS1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T60529-Ag, GM-Tg-rg-T60529-Ag, GM-Tg-mg-T60529-Ag, GM-Tg-cynog-T60529-Ag, GM-Tg-felg-T60529-Ag, GM-Tg-cang-T60529-Ag, GM-Tg-bovg-T60529-Ag, GM-Tg-equg-T60529-Ag-1
Products Name	COX-1/PTGS1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	COX-1
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX-1/PTGS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.