Recombinant multi-species SOST/ CDD/ DAND61 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOST protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SOST, gene name: SOST, also named as CDD, DAND61, VBCH, SOST. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T60724-Ag-1	Human SOST protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T60724-Ag-1	Rat SOST protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T60724-Ag-1	Mouse SOST protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T60724-Ag-1	Cynomolgus/ Rhesus macaque SOST protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T60724-Ag-1	Feline SOST protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T60724-Ag-1	Canine SOST protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T60724-Ag-1	Bovine SOST protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T60724-Ag-1	Equine SOST protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T60724-Ag, GM-Tg-rg-T60724-Ag, GM-Tg-mg-T60724-Ag, GM-Tg-cynog-T60724-Ag, GM-Tg-felg-T60724-Ag, GM-Tg-cang-T60724-Ag, GM-Tg-bovg-T60724-Ag, GM-Tg-equg-T60724-Ag-1
Products Name	SOST protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	SOST
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOST protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.