Recombinant multi-species MCR/ NR3C2/ MLR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NR3C2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: NR3C2, gene name: NR3C2, also named as MCR, MLR, MRVIT, NR3C2. This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T63179-Ag-1	Human NR3C2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T63179-Ag-1	Rat NR3C2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T63179-Ag-1	Mouse NR3C2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T63179-Ag-1	Cynomolgus/ Rhesus macaque NR3C2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T63179-Ag-1	Feline NR3C2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T63179-Ag-1	Canine NR3C2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T63179-Ag-1	Bovine NR3C2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T63179-Ag-1	Equine NR3C2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T63179-Ag, GM-Tg-rg-T63179-Ag, GM-Tg-mg-T63179-Ag, GM-Tg-cynog-T63179-Ag, GM-Tg-felg-T63179-Ag, GM-Tg-cang-T63179-Ag, GM-Tg-bovg-T63179-Ag, GM-Tg-equg-T63179-Ag-1
Products Name	NR3C2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	NR3C2
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NR3C2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.