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Recombinant multi-species RNF34/ CARP-1/ CARP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to RNF34/RNF34 products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF34 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: RNF34, gene name: RNF34, also named as CARP-1, CARP1, RFI, RIF, RIFF, hRFI. The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-T68265-Ag-1 | Human RNF34 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T68265-Ag-1 | Rat RNF34 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T68265-Ag-1 | Mouse RNF34 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T68265-Ag-1 | Cynomolgus/ Rhesus macaque RNF34 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-T68265-Ag-1 | Feline RNF34 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-T68265-Ag-1 | Canine RNF34 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T68265-Ag-1 | Bovine RNF34 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T68265-Ag-1 | Equine RNF34 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-T68265-Ag, GM-Tg-rg-T68265-Ag, GM-Tg-mg-T68265-Ag, GM-Tg-cynog-T68265-Ag, GM-Tg-felg-T68265-Ag, GM-Tg-cang-T68265-Ag, GM-Tg-bovg-T68265-Ag, GM-Tg-equg-T68265-Ag-1 |
| Products Name | RNF34 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RNF34 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF34 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
