Recombinant multi-species CXL11/ CXCL11/ H174 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CXCL11, gene name: CXCL11, also named as H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1. Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T68465-Ag-1	Human CXCL11 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T68465-Ag-1	Rat CXCL11 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T68465-Ag-1	Mouse CXCL11 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T68465-Ag-1	Cynomolgus/ Rhesus macaque CXCL11 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T68465-Ag-1	Feline CXCL11 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T68465-Ag-1	Canine CXCL11 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T68465-Ag-1	Bovine CXCL11 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T68465-Ag-1	Equine CXCL11 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T68465-Ag, GM-Tg-rg-T68465-Ag, GM-Tg-mg-T68465-Ag, GM-Tg-cynog-T68465-Ag, GM-Tg-felg-T68465-Ag, GM-Tg-cang-T68465-Ag, GM-Tg-bovg-T68465-Ag, GM-Tg-equg-T68465-Ag-1
Products Name	CXCL11 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	CXCL11
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.