Recombinant multi-species GA45B/ GADD45B/ GADD45BETA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to GADD45B/GADD45B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GADD45B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GADD45B, gene name: GADD45B, also named as GADD45BETA, MYD118. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway.  This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T70797-Ag-1Human GADD45B proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T70797-Ag-1Rat GADD45B proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T70797-Ag-1Mouse GADD45B proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T70797-Ag-1Cynomolgus/ Rhesus macaque GADD45B proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T70797-Ag-1Feline GADD45B proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T70797-Ag-1Canine GADD45B proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T70797-Ag-1Bovine GADD45B proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T70797-Ag-1Equine GADD45B proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T70797-Ag, GM-Tg-rg-T70797-Ag, GM-Tg-mg-T70797-Ag, GM-Tg-cynog-T70797-Ag,
GM-Tg-felg-T70797-Ag, GM-Tg-cang-T70797-Ag, GM-Tg-bovg-T70797-Ag, GM-Tg-equg-T70797-Ag-1
Products Name GADD45B protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameGADD45B
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GADD45B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.