Recombinant multi-species CFAH/ CFH/ AHUS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CFH/CFH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CFH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CFH, gene name: CFH, also named as AHUS1, AMBP1, ARMD4, ARMS1L3, FH, FHL1, HF, HF1, HF2, HUS, CFH. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T71086-Ag-1Human CFH proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T71086-Ag-1Rat CFH proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T71086-Ag-1Mouse CFH proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T71086-Ag-1Cynomolgus/ Rhesus macaque CFH proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T71086-Ag-1Feline CFH proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T71086-Ag-1Canine CFH proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T71086-Ag-1Bovine CFH proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T71086-Ag-1Equine CFH proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T71086-Ag, GM-Tg-rg-T71086-Ag, GM-Tg-mg-T71086-Ag, GM-Tg-cynog-T71086-Ag,
GM-Tg-felg-T71086-Ag, GM-Tg-cang-T71086-Ag, GM-Tg-bovg-T71086-Ag, GM-Tg-equg-T71086-Ag-1
Products Name CFH protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCFH
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CFH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.